These are people I have worked with, they sell quality products, for the best prices and stand behind what they sell.
They will also give you 5% off on purchases if you use code Fred Seton for a reference.
Using a design, with loops up to 500' of 1/2" pex with a single manifold next to the heater in the mechanical area will heat very large homes. This design allows as many thermostat controlled zones as you need. It eliminates using a pump for each thermostat and manifolds scattered throughout the home.
USING A SINGLE PUMP AND ZONE VALVES FOR EACH ZONE IS THE SIMPLEST AND MOST EFFICIENT SYSTEM.